Which disease is a chronic autoimmune inflammatory disease of skin, joints, and internal organs?

Which disease is a chronic autoimmune inflammatory disease of skin, joints, and internal organs?

• A. Chronic fatigue syndrome
• B. Systemic lupus erythematosus
• C. Mononucleosis
• D. Lymphedema

Answer: (B)

Systemic lupus erythematosus is a chronic autoimmune condition in which the immune system mistakenly attacks the body's own tissues, leading to inflammation that can involve the skin, joints, and internal organs. This multi-organ involvement is a hallmark, with skin manifestations such as a malar or photosensitive rash, joint inflammation (arthritis), and potential impact on kidneys, heart, lungs, and more. The presence of autoantibodies, like antinuclear antibodies, reflects the autoimmune nature and helps explain why symptoms can be widespread and variable over time. The other conditions don’t fit this pattern. Chronic fatigue syndrome centers on persistent fatigue with no specific autoimmune-driven inflammation of skin or organs. Mononucleosis is an infectious illness caused by EBV. Lymphedema is swelling from lymphatic obstruction, not autoimmune inflammation of multiple organs.

Systemic lupus erythematosus is a chronic autoimmune condition in which the immune system mistakenly attacks the body's own tissues, leading to inflammation that can involve the skin, joints, and internal organs. This multi-organ involvement is a hallmark, with skin manifestations such as a malar or photosensitive rash, joint inflammation (arthritis), and potential impact on kidneys, heart, lungs, and more. The presence of autoantibodies, like antinuclear antibodies, reflects the autoimmune nature and helps explain why symptoms can be widespread and variable over time.

The other conditions don’t fit this pattern. Chronic fatigue syndrome centers on persistent fatigue with no specific autoimmune-driven inflammation of skin or organs. Mononucleosis is an infectious illness caused by EBV. Lymphedema is swelling from lymphatic obstruction, not autoimmune inflammation of multiple organs.